Zeo Choy
PhD / Bioinformatician / AI & ML
Biography
Highly motivated individual with a deep interest in leveraging artificial intelligence for precision medicine. My focus lies in applying bioinformatics & AI/ML techniques to analyze biological problems and next-generation sequencing (NGS) data.
My skillset combines technical expertise with hands on wet lab experience. I’m proficient in common AI/ML frameworks and possess a strong understanding of NGS data processing pipelines, variant calling, and functional genomics analysis. Additionally, I have a solid foundation in molecular biology techniques, cell culture, and in vitro drug assays.
I’m driven by the transformative potential of AI in the realm of precision medicine. I believe the synergy of deep learning and NGS data holds the key to unlocking novel diseases diagnoses and treatment strategies.
- Bioinformatics
- AI/ML
- NGS
- Precision Medicine
- Molecular Diagnostics
- Cancer
- Microbiome
PhD in Medical Sciences, 2019
The Chinese University of Hong Kong
MPhil in Medical Sciences, 2016
The Chinese University of Hong Kong
BEng in Biomedical Engineering, 2014
The Chinese University of Hong Kong
Skills
- Data: WGS, WES, RNA-Seq, targeted resequencing, 16S/shotgun microbiome
- Database: GEO, TCGA, PCAWG, COSMIC, dbSNP, gnomAD, ClinVar, OncoKB, CCLE, LINCS, SILVA, Greengenes etc.
- Analysis: biological data mining, biomarkers discovery, molecular subtyping, survival analysis, differential abundance analysis, network inference etc.
- Pipeline: GATK, DRAGEN, QIIME2/PICRUSt, kneadData/MetaPhlAn/HUMAnN
- Experience in variant interpretation using ACGS, ACMG, AMP guidelines
- Lanuages: Python, R, Shell, SQL
- Frameworks: Django, Flask, Streamlit, HTML, Bootstrap, JavaScript, SQL, C++
- Platform: Linux, Mac, Windows, AWS and GCP
Data wrangling, model training, data visualisation, database managment
NGS, PCR (PCR, qPCR, dPCR), cloning, immunostaining (IF/ICC/IHC), western blotting, flow cytometry
Clinical Validation (CAP, ISO)
Cell lines, Organoids, Mouse Xenograft
Experience
- Develop technical aspects of the company’s strategy to ensure alignment with its business goals
- Discover and implement new technologies that yield competitive advantage
- Communicate technology strategy to partners and investors
- In charge of the research logistics, coordination, timeline, manuscript preparation and bioinformatics analysis for microbiome research projects
- Leaded the R&D team and interns to prepare scientifically driven materials to support sales & marketing activities
- Assisted the senior officers in planning and setting up a new molecular laboratory supporting population genome project
- Prepared reporting guidelines and internal training materials for data interpretation and genome analysis
- Provided bioinformatics support (including QA/QC, data analysis, management, and interpretation) for clinical reporting of NGS data
- Leaded and planned various cancer research projects ($10m funding)
Accomplishments
Recent Publications
Projects
